Glucophage ®
Original metformin
The world’s most prescribed oral antidiabetic,1 used as the first line treatment for type 2 diabetes in all major guidelines.4,5,6 Glucophage® is an immediate release tablet, which is taken two or three times a day either during or just after meals. The formulation is available in doses of 500mg, 850mg and 1000mg tablets.
INDICATIONS
Treatment of type 2 diabetes mellitus, especially in obese patients, when diet and exercise do not result in adequate glycemic control.
In adults
Glucophage can be used alone or in combination with other oral antidiabetic agents or insulin.
In children
from the age of 10 and adolescents Glucophage can be used as monotherapy or in combination with insulin.
Reduction of diabetic complications in metformin-type 2 diabetic patients treated as primary treatment after diet failure
- NICE guideline ph38: Type 2 diabetes: prevention in people at high risk. Published 12 July 2012. Available at: https://www.nice.org.uk/guidance/ph38/chapter/8-glossary#pre-diabetes. Last accessed March 2018.
- ADA (American Diabetes Association). Standards of Medical Care in Diabetes. Diabetes Care. 2013;36(1):S11 66.
- IDF (International Diabetes Federation). (2012). Clinical Guidelines Task Force: Global guideline for the management of type 2 diabetes. Available at: https://www.idf.org/e-library/guidelines/79-global-guideline-for-type-2-diabetes Last accessed March 2018.
- DPP Research Group. Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin. N Engl J Med. 2002;346:393 403.
- ESC (European Society of Cardiology). Diabetes, Prediabetes and Cardiovascular Diseases with the EASD. Available at: https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Diabetes-Pre-Diabetes-and-Cardiovascular-Diseases-developed-with-the-EASD. Last accessed November 2017
- SMC. UK 2017. Glucophage SR 500mg, 750mg and 1000mg prolonged release tablets.